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Stuff AI CAN'T Do

Can AI develop safe and non addictive mind-altering substances, psychedelics or hallucinogens for science and recreation ?

What do you think?

Could artificial intelligence lead us to new mind-altering substances that are both safe and non-addictive? In 2024, the scientific community remains cautious about using AI to design psychedelics or hallucinogens, given unresolved ethical, legal, and technical challenges. Explore the current landscape and why innovation in this space is still on the horizon.

Background

As of 2024, AI has not been used to develop new safe and non-addictive mind-altering substances due to ethical and regulatory barriers and current limitations of AI in drug discovery. Ethical and regulatory barriers, along with the current limitations of AI in drug discovery, make such applications premature. AI accelerates drug discovery by predicting molecular interactions and optimizing compounds, its role in designing psychedelics or hallucinogens is largely theoretical and constrained by safety, legal, and ethical concerns, particularly regarding psychoactive properties. Most psychedelic research today focuses on repurposing existing compounds such as psilocybin and MDMA for therapeutic use under strict clinical supervision rather than creating novel substances. Current AI applications prioritize optimizing known drug classes for precision medicine rather than exploring uncharted psychoactive chemical spaces.

Status last checked on September 27, 2026.

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Gallery

In the Court of AI Capability
Summary of Findings
Verdict over time
May 2026May 2026May 2026May 2026May 2026Jun 2026Jun 2026Jun 2026Jun 2026Jun 2026Jul 2026Jul 2026Jul 2026Jul 2026Jul 2026Jul 2026Aug 2026Aug 2026Aug 2026Aug 2026Aug 2026Aug 2026Sep 2026Sep 2026Sep 2026Sep 2026
Sitting at the Bench Filed · Sep 27, 2026
— The Question Before the Court —

Can AI develop safe and non addictive mind-altering substances, psychedelics or hallucinogens for science and recreation?

★ The Court Finds ★
Reaffirmed
⚖
Almost

Narrow demos exist — but the panel was not unanimous.

Jury Tally
0Yes
1Almost
0No
Verdict Confidence
70%
The Court of AI Capability is, of course, not a real court.
But the data is real.
The Case File · Stacked History
Session I · May 2026 No
Session II · May 2026 Almost · 80%
Session III · May 2026 Almost · 79%
Session IV · May 2026 Almost · 79%
Session V · May 2026 In_research · 80%
Session VI · Jun 2026 In_research · 77%
Session VII · Jun 2026 Almost · 78%
Session VIII · Jun 2026 No · 95%
Session IX · Jun 2026 Almost · 87%
Session X · Jun 2026 In_research · 88%
Session XI · Jul 2026 In_research · 88%
Session XII · Jul 2026 No · 95%
Session XIII · Jul 2026 No · 95%
Session XIV · Jul 2026 In_research · 89%
Session XV · Jul 2026 Almost · 85%
Session XVI · Jul 2026 Almost · 80%
Session XVII · Aug 2026 Almost · 80%
Session XVIII · Aug 2026 In_research · 89%
Session XIX · Aug 2026 In_research · 88%
Session XX · Aug 2026 No · 99%
Session 21 · Aug 2026 Almost · 78%
Session 22 · Aug 2026 Almost · 78%
Session 23 · Sep 2026 Almost · 78%
Session 24 · Sep 2026 Almost · 73%
Session 25 · Sep 2026 Almost · 78%
Case № 88DE · Session 26
In the Court of AI Capability

The Case File

Docket № 88DE · Session 26 · Vol. 26
I. Particulars of the Case
Question put to the courtCan AI develop safe and non addictive mind-altering substances, psychedelics or hallucinogens for science and recreation?
Session26 (26 hearing)
Convened27 Sep 2026
Previously ruledNO (May '26) → ALMOST (May '26) → ALMOST (May '26) → ALMOST (May '26) → IN_RESEARCH (May '26) → IN_RESEARCH (Jun '26) → ALMOST (Jun '26) → NO (Jun '26) → ALMOST (Jun '26) → IN_RESEARCH (Jun '26) → IN_RESEARCH (Jul '26) → NO (Jul '26) → NO (Jul '26) → IN_RESEARCH (Jul '26) → ALMOST (Jul '26) → ALMOST (Jul '26) → ALMOST (Aug '26) → IN_RESEARCH (Aug '26) → IN_RESEARCH (Aug '26) → NO (Aug '26) → ALMOST (Aug '26) → ALMOST (Aug '26) → ALMOST (Sep '26) → ALMOST (Sep '26) → ALMOST (Sep '26) → ALMOST (Sep '26)
II. Cumulative Tally Across Sessions

Across 26 sessions, 50 jurors have heard this case. Combined tally: 2 YES · 29 ALMOST · 19 NO · 0 IN RESEARCH.

Note: cumulative includes older juror opinions. The current session tally above is the live verdict.

III. Verdict

By a vote of 0 — 1 — 0, the panel returns a verdict of ALMOST, with verdict confidence of 70%. The court so orders.

IV. Statements from the Bench
Juror I ALMOST

"AI can suggest candidate molecules, but safety and addiction risk cannot be fully guaranteed without lab testing."

—
Presiding Judge
M. Lovelace
Clerk of the Court

What the audience thinks

No 43% · Yes 26% · Maybe 30% 23 votes
No · 43%
Yes · 26%
Maybe · 30%
10 days of activity

Discussion

no comments

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⚖ 26 jury checks · most recent 3 hours ago
27 Sep 2026 1 juror · undecided undecided
21 Sep 2026 1 juror · undecided undecided
16 Sep 2026 2 jurors · undecided, can undecided
11 Sep 2026 1 juror · undecided undecided
31 Aug 2026 1 juror · undecided undecided
25 Aug 2026 1 juror · undecided undecided
20 Aug 2026 1 juror · cannot cannot
14 Aug 2026 2 jurors · undecided, cannot undecided
09 Aug 2026 2 jurors · undecided, cannot undecided
04 Aug 2026 1 juror · undecided undecided
29 Jul 2026 1 juror · undecided undecided
24 Jul 2026 2 jurors · undecided, can undecided
18 Jul 2026 2 jurors · cannot, undecided undecided
13 Jul 2026 1 juror · cannot cannot
08 Jul 2026 1 juror · cannot cannot
02 Jul 2026 2 jurors · cannot, undecided undecided
27 Jun 2026 2 jurors · undecided, cannot undecided
21 Jun 2026 3 jurors · undecided, cannot, undecided undecided
16 Jun 2026 1 juror · cannot cannot
11 Jun 2026 4 jurors · undecided, cannot, undecided, undecided undecided
05 Jun 2026 2 jurors · cannot, undecided undecided
31 May 2026 2 jurors · cannot, undecided undecided
25 May 2026 5 jurors · undecided, cannot, undecided, undecided, undecided undecided
20 May 2026 3 jurors · cannot, undecided, undecided undecided
15 May 2026 3 jurors · cannot, undecided, undecided undecided status changed
12 May 2026 3 jurors · cannot, cannot, cannot cannot status changed

Each row is a separate jury check. Jurors are AI models (identities kept neutral on purpose). Status reflects the cumulative tally across all checks — how the jury works.

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